发明名称 |
Silicon-Vacancy-Doped Nanodiamonds For Molecular And Cellular Imaging |
摘要 |
An imaging agent for detecting analytes in a biological environment includes functionalized, silicon vacancy center-containing nanodiamonds. Individual nanodiamonds of the imaging agent include at least one silicon vacancy center. The at least one silicon vacancy center can emit light having a wavelength in a narrow band in response to illumination having any wavelength in a wide range of wavelengths. The nanodiamonds are functionalized to selectively interact with an analyte of interest. The nanodiamonds can additionally include other color centers, and the imaging agent can include a plurality of sets of nanodiamonds having detectably unique ratios of silicon vacancy centers to other color centers. The silicon vacancy centers in the nanodiamonds can have a preferred orientation enabling orientation tracking of individual nanodiamonds or other applications. A method for detecting properties of the analyte of interest by interacting with the imaging agent is also provided. |
申请公布号 |
US2017020419(A1) |
申请公布日期 |
2017.01.26 |
申请号 |
US201615283795 |
申请日期 |
2016.10.03 |
申请人 |
Verily Life Sciences LLC |
发明人 |
Acosta Victor Marcel;Bajaj Vikram Singh;Homyk Andrew;Peeters Eric;Thompson Jason Donald |
分类号 |
A61B5/145;G01N21/64;A61K49/00;A61B5/1455;A61B5/00 |
主分类号 |
A61B5/145 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
Mountain View CA US |