发明名称 METHODS OF INHIBITING TUMOR GROWTH BY ANTAGONIZING IL-6 RECEPTOR
摘要 The present invention provides methods for inhibiting or attenuating tumor growth in a subject by administering an IL-6 antagonist to the subject. In certain embodiments, the methods of the invention are used to inhibit the growth of an anti-VEGF-resistant tumor in a subject. The IL-6 antagonist may be, e.g., an antibody that specifically binds IL-6R. The IL-6 antagonist may be administered in combination with a VEGF antagonist, and/or an EGFR antagonist.
申请公布号 US2017022279(A1) 申请公布日期 2017.01.26
申请号 US201615204639 申请日期 2016.07.07
申请人 REGENERON PHARMACEUTICALS, INC. 发明人 ZHANG Li
分类号 C07K16/28;C07K16/32;A61K39/395 主分类号 C07K16/28
代理机构 代理人
主权项
地址 Tarrytown NY US