ZOLPIDEM COMPOSITION AND PROCESS FOR PREPARING THE SAME

摘要

Disclosed is a zolpidem composition and a process for preparing the same. The zolpidem composition comprises: zolpidem tartrate and polacrillin potassium in a weight ratio of 1:8. The process for preparation of a zolpidem composition comprises: mixing zolpidem tartrate and polacrillin potassium in a weight ratio of 1:8 to form a taste masked dry mix; mixing the pharmaburst B2, lactose monohydrate, colloidal silicon dioxide anhydrous, a sweetener, and a flavorant to form a flavor blend; blending of the taste masked dry mix and the flavor blend to form an intermediate blend; mixing of intermediate blend with magnesium stearate to form ready to compress granules of the zolpidem composition; and compressing the ready to compress granules of the zolpidem composition to form a sublingual oral disintegrating tablet.