LOW-VOLUME COAGULATION ASSAY

摘要

Compositions and methods for measuring coagulation parameters using very small volumes of blood are provided. Advantageously, the methods described herein can be performed from a single drop of blood (about 20 μL) while generally leaving enough sample to perform other measurements, optionally in a multiplexed format. The methods and devices do not require a skilled operator and can be performed at the point of service, which can be an important feature for managing blood coagulation disorders and treatments thereof.

主权项

1. A method for measuring coagulation time of a blood sample of a subject, comprising:
(a) initiating a coagulation reaction of the blood sample of the subject; (b) obtaining a set of more than one image of said coagulation reaction; and (c) analyzing said set of images to measure the coagulation time of said blood sample.