The disclosure provides amino acid sequence variants of Bacillus thuringiensis (Bt) toxins and methods of producing the same. Some aspects of this disclosure provide methods for generating Bt toxin variants by continuous directed evolution. Some aspects of this disclosure provide compositions and methods for pest control using the disclosed variant Bt toxins.
申请公布号
WO2017015559(A2)
申请公布日期
2017.01.26
申请号
WO2016US43559
申请日期
2016.07.22
申请人
PRESIDENT AND FELLOWS OF HARVARD COLLEGE;MONSANTO COMPANY