| 发明名称 |
Factor VIII Molecules with Reduced VWF Binding |
| 摘要 |
The present invention relates to a recombinant Factor VIII molecule, wherein said molecule has reduced vWF binding capacity, and wherein said molecule is covalently conjugated with at least one side group. |
| 申请公布号 |
US2017020992(A1) |
申请公布日期 |
2017.01.26 |
| 申请号 |
US201615288248 |
申请日期 |
2016.10.07 |
| 申请人 |
Novo Nordisk A/S |
发明人 |
Bolt Gert;Peschke Bernd;Kofod-Hansen Mikael;Buchardt Jens;Stennicke Henning Ralf;Oestergaard Henrik;Kjalke Marianne;Olsen Eva H. Norling;Hansen Jens Jacob;Zundel Magali |
| 分类号 |
A61K38/37;C07K14/755;A61K47/48 |
主分类号 |
A61K38/37 |
| 代理机构 |
|
代理人 |
|
| 主权项 |
1. A recombinant Factor VIII molecule, wherein said molecule has reduced vWF binding capacity, and wherein said molecule is covalently conjugated with at least one side group. |
| 地址 |
Bagsvaerd DK |
