发明名称 CHIRAL DIARYL MACROCYCLES AND USES THEREOF
摘要 This disclosure relates to the use of certain diaryl macrocycle compounds, specifically (7S13R)-11-fluoro-7,13-dimethyl-6,7,13,14-tetrahydro-1,15-ethenopyrazolo[4,3-f][1,4,8,10]benzoxatriazacyclotridecin-4(5H)-one in the treatment of disease in mammals. This disclosure also relates to compositions including such compounds, and to methods of using such compositions in the treatment of diseases in mammals, especially in humans.
申请公布号 WO2017015367(A1) 申请公布日期 2017.01.26
申请号 WO2016US43132 申请日期 2016.07.20
申请人 TP THERAPEUTICS, INC. 发明人 CUI, Jingrong Jean;LI, Yishan;ROGERS, Evan W.;ZHAI, Dayong;DENG, Wei;HUANG, Zhongdong
分类号 C07D491/16;A61K31/519;A61K31/52;C07D491/12;C07D491/18;C07D498/18 主分类号 C07D491/16
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