PROCESS FOR PRODUCTION OF HALOGENATED ALPHA-FLUOROETHERS

摘要

Halogenated ±-fluoroethers (or bis-derivatives thereof) can be produced by reacting a halogenated hemiacetal (or bis-derivative thereof) with sulfuryl fluoride (SO 2 F 2 ) in the presence of an organic base. The reaction is conducted preferably in the presence of "a salt or complex of an organic base with hydrogen fluoride", whereby the objective dehydroxyfluorination can proceed extremely favorably. It is still preferable to use as the starting substrate a halogenated hemiacetal prepared from fluoral or 3,3,3-trifluoropyruvic acid ester. Thus, industrially important halogenated ±-fluoroethers can be industrially produced with high selectivity and in high yield.