发明名称 |
OIL/SURFACTANT MIXTURES FOR SELF-EMULSIFICATION |
摘要 |
Oil-in-water emulsions with small droplet sizes can be formed without requiring either microfluidisation or heating to cause phase inversion, but rather by simple mixing of a pre-mixed composition of oil and a surfactant component comprising at least one surfactant component with aqueous material. The HLB value of the surfactant component can be selected to give a composition which, on mixing with a volume excess of aqueous material, spontaneously forms an oil in water emulsion with submicron oil droplets having a diameter <250 nm, suitable for filter sterilisation. Droplet diameters of <40 nm can also be achieved. |
申请公布号 |
EP3119430(A1) |
申请公布日期 |
2017.01.25 |
申请号 |
EP20150709964 |
申请日期 |
2015.03.17 |
申请人 |
GlaxoSmithKline Biologicals S.A. |
发明人 |
BRITO, Luis;DODD, Stephanie Kay;O'HAGAN, Derek;SINGH, Manmohan |
分类号 |
A61K39/39;A61K9/107 |
主分类号 |
A61K39/39 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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