发明名称 |
AMYLOID TARGETING AGENTS AND METHODS OF USING THE SAME |
摘要 |
Provided herein is the design and synthesis of novel molecular rotor fluorophores useful for detection of amyloid or amyloid like proteins. The fluorophores are designed to exhibit enhanced fluorescence emission upon associating with amyloid or amyloid like proteins as compared to unbound compound. Also disclosed herein are the methods for treating of diseases associated with an amyloid or amyloid like proteins. |
申请公布号 |
EP3119761(A1) |
申请公布日期 |
2017.01.25 |
申请号 |
EP20150714358 |
申请日期 |
2015.03.19 |
申请人 |
Amydis Diagnostics, Inc.;The Regents of the University of California |
发明人 |
YANG, Jerry;THEODORAKIS, Emmanuel, A.;SARRAF, Stella |
分类号 |
C07D401/14;C07C255/58;C07C255/59;C07C311/35;C07D241/04;C07D333/22;C07D401/04;C07D405/04;C07D405/10;C07D407/10;C07D409/04;C07D409/10;C07D409/14;C07H13/00;C07H13/04 |
主分类号 |
C07D401/14 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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