发明名称 |
PYRIDONEMORPHINAN ANALOGS AND BIOLOGICAL ACTIVITY ON OPIOID RECEPTORS |
摘要 |
The application is directed to compounds of Formula I-A and pharmaceutically acceptable salts and solvates thereof, wherein , R1a—R3a, R4, Y and Za are defined as set forth in the specification. The invention is also directed to use of compounds of Formula I-A to treat disorders responsive to the modulation of one or more opioid receptors, or as synthetic intermediates. Certain compounds of the present invention are especially useful for treating pain. |
申请公布号 |
EP2931724(B1) |
申请公布日期 |
2017.01.25 |
申请号 |
EP20130820881 |
申请日期 |
2013.12.13 |
申请人 |
Purdue Pharma LP |
发明人 |
TAFESSE, Laykea;LOCKMAN, Jeffrey;YOUNGMAN, Mark, A. |
分类号 |
C07D471/08;C07D471/18;C07D471/22;C07D519/00 |
主分类号 |
C07D471/08 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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