发明名称 |
NEW NEURONAL VIABILITY FACTOR AND ITS USE FOR TREATING CONE DYSTROPHY |
摘要 |
The present invention concerns a pharmaceutical composition comprising a pharmaceutically acceptable carrier and a compound selected in the group comprising (i) a polypeptide comprising an amino acid sequence selected in the group comprising the amino acid sequence of the short isoform in Homo sapiens of the RdCVF2 gene (SEQ ID NO:1), orthologs, derivatives and fragments thereof, (ii) a polynucleotide coding for said polypeptide, (iii) a vector comprising said polynucleotide, and (iv) a host cell genetically engineered expressing said polypeptide; the use of such a composition for the manufacture of a medicament for treating and/or preventing a neurodegenerative disorder in a subject; and a method of testing a subject thought to have or be predisposed to having a neurodegenerative disorder. |
申请公布号 |
EP2175932(B1) |
申请公布日期 |
2017.01.25 |
申请号 |
EP20080760606 |
申请日期 |
2008.06.05 |
申请人 |
Institut National de la Santé et de la Recherche Médicale (INSERM);Centre National de la Recherche Scientifique (C.N.R.S.) |
发明人 |
LEVEILLARD, Thierry;SAHEL, José-Alain;JAILLARD, Céline;POCH, Olivier |
分类号 |
A61P25/28;C12N15/85;G01N33/68 |
主分类号 |
A61P25/28 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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