发明名称 |
AMINOPYRIMIDINE DERIVATIVES AS LRRK2 MODULATORS |
摘要 |
Compounds of the formula I:
or pharmaceutically acceptable salts thereof,
wherein A, X, R 1 , R 2 , R 3 and R 4 are as defined herein. Also disclosed are methods of making the compounds and using the compounds for treatment of diseases associated with LRRK2 receptor, such as Parkinson's disease. |
申请公布号 |
EP3121173(A1) |
申请公布日期 |
2017.01.25 |
申请号 |
EP20160180049 |
申请日期 |
2012.11.28 |
申请人 |
F. Hoffmann-La Roche AG |
发明人 |
BAKER-GLENN, Charles;CHAMBERS, Mark;CHAN, Bryan K.;ESTRADA, Anthony;SWEENEY, Zachary Kevin |
分类号 |
C07D401/12;A61K31/506;A61K31/5377;A61K31/538;A61K31/553;A61P25/16;C07D403/12;C07D403/14;C07D405/12;C07D405/14;C07D413/12;C07D413/14 |
主分类号 |
C07D401/12 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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