主权项 |
1. A solvate of N-(2,4-di-tert-butyl-5-hydroxyphenyl-1, 4-dihydro-4-oxoquiniline-3-carboxamide, a compound of formula I,wherein the solvate is selected from a crystalline N-(2,4-di-tert-butyl-5-hydroxyphenyl)-1, 4-dihydro-4-oxoquiniline-3-carboxamide.n-butanol solvate characterized by X-ray Diffraction (XRD) spectrum having peak reflections at about 3.4 and 14.2±0.2 degrees 2 theta or a crystalline N-(2,4-di-tert-butyl-5-hydroxyphenyl)-1, 4-dihydro-4-oxoquiniline-3-carboxamide.methanol solvate characterized by X-ray Diffraction (XRD) spectrum having peak reflections at about 7.28, 13.84, 14.03, 19.78, 20.27 and 20.92±0.2 degrees 2 theta. |