| 发明名称 | Methods and compositions for detecting pathogenic bacteria | ||
| 摘要 | The present invention encompasses methods and compositions for detecting pathogenic bacteria. Additionally, the present invention encompasses methods and compositions for catalyzing the dismutation of superoxide radicals. Further, the present invention encompasses methods for determining the antibiotic susceptibility of pathogenic bacteria. | ||
| 申请公布号 | US9551021(B2) | 申请公布日期 | 2017.01.24 |
| 申请号 | US201514689868 | 申请日期 | 2015.04.17 |
| 申请人 | WASHINGTON UNIVERSITY | 发明人 | Henderson Jeffrey P.;Hung Chia;Chaturvedi Kaveri |
| 分类号 | A61K39/00;C07K14/24;C12Q1/00;C12Q1/10;G01N33/569 | 主分类号 | A61K39/00 |
| 代理机构 | Polsinelli PC | 代理人 | Polsinelli PC |
| 主权项 | 1. A method for detecting the presence of yersiniabactin-expressing bacteria in a subject, the method comprising the steps of: a) obtaining a sample from the subject; b) analyzing the sample, in vitro, by mass spectrometry for the presence or absence of hydroxyphenyl-thiazolinyl-thiazolinyl (HPTT), wherein the detection of a peak with m/z 307 detects HPTT; and c) identifying the presence of yersiniabactin-expressing bacteria in the subject when HPTT is present in the sample. | ||
| 地址 | St. Louis MO US | ||