Methods, systems, and devices for tissue characterization and quantification using intravascular ultrasound signals

摘要

A method of evaluating at least one tissue type includes providing a tissue classifier comprising multiple detector arrays for each of multiple tissue types. Each detector array comprises multiple detectors and each detector comprises multiple tissue type-assigned intravascular ultrasound (IVUS) spectra. For each of the detector arrays, an input IVUS spectrum of the tissue region is compared to the tissue type-assigned IVUS spectra of each of the detectors in the detector array and it is determined whether the input spectrum corresponds to the tissue type of the detector. The results for the detector. The results for the detector arrays are combined to provide a tissue characterization of the tissue region from the multiple tissue types. One or more IVUS images can be displayed with the tissue characterization and an indication of the size of at least one of the tissue types in a selected portion of the image that is displayed.

主权项

1. A method of evaluating at least one tissue type in at least one intravascular ultrasound (IVUS) image, the method comprising:
a) providing a tissue classifier comprising a plurality of detector arrays for each of a plurality of tissue types, wherein each detector array comprises a plurality of detectors and each detector comprises a plurality of tissue type-assigned IVUS spectra, wherein a plurality of the tissue type-assigned IVUS spectra of each detector correspond to a tissue type of the detector and a plurality of the tissue type-assigned IVUS spectra correspond to other tissue types; b) comparing an input IVUS spectrum of a region in the at least one intravascular ultrasound image to the tissue type-assigned IVUS spectra of each of the plurality of detectors for each of the plurality of detector arrays; c) determining, for each of the plurality of detectors of each of the plurality of detector arrays, whether the input IVUS spectrum corresponds to the tissue type of the detector based on the comparisons of the input IVUS spectrum to the tissue type-assigned IVUS spectra for that detector; d) for each of the plurality of detector arrays, combining results of the plurality of detectors of the detector array to produce an array result; e) combining the array results for the plurality of detector arrays to provide a tissue characterization of the region from the plurality of tissue types; f) repeating b) to e) for each region to be characterized in the at least one intravascular ultrasound image; g) determining a size of at least one of the tissue types in a selected portion of the at least one intravascular ultrasound image using the tissue characterizations of the regions in the selected portion; and h) displaying one or more of the at least one intravascular ultrasound image with an indication of the tissue characterization of one or more regions of the at least one intravascular ultrasound image that is displayed and an indication of the size of at least one of the tissue types in the selected portion of the at least one intravascular ultrasound image that is displayed.