Macrocyclic picolinamide compounds with fungicidal activity

摘要

The invention relates to macrocyclic picolinamides of Formula I and their use as fungicides.;

主权项

1. A compound of Formula I wherein X is hydrogen or C(O)R3; Y is hydrogen, C(O)R3, or Q; Q is R1 is hydrogen, alkyl, alkenyl, aryl, alkoxy, or acyl, each optionally substituted with 0, 1 or multiple R6; R2 is hydrogen, alkyl, acyl, aryl, alkenyl, or —Si(R5)3, each optionally substituted with 0, 1 or multiple R6; R3 is alkoxy or benzyloxy, each optionally substituted with 0, 1, or multiple R6; R4 is hydrogen, —C(O)R5, or —CH2OC(O)R5; R5 is alkyl, alkoxy, or aryl, each optionally substituted with 0, 1, or multiple R6; R6 is hydrogen, alkyl, aryl, acyl, halo, alkenyl, alkoxy, or thioalkyl, each optionally substituted with 0, 1, or multiple R7; and R7 is hydrogen, alkyl, aryl, or halo; wherein acyl refers to —C(═O)-cyclopropyl or —C(═O)—CH(CH3)2.