发明名称 |
Genetically enhanced cyanobacteria for the production of a first chemical compound harbouring Zn<sup>2+</sup>, Co<sup>2+</sup> or Ni<sup>2+</sup> -inducible promoters |
摘要 |
One embodiment of the invention is directed to a genetically enhanced cyanobacterium for the production of a first chemical compound, comprising at least one first recombinant gene encoding a first biocatalyst for the production of the first chemical compound, wherein the gene is under the transcriptional control of a Co2+ or Zn2+-inducible promoter. Such a cyanobacterium can provide a tighter control of the production of the first chemical compound. |
申请公布号 |
US9551014(B2) |
申请公布日期 |
2017.01.24 |
申请号 |
US201414320569 |
申请日期 |
2014.06.30 |
申请人 |
Algenol Biotech LLC |
发明人 |
Dühring Ulf;Baier Kerstin;Germer Frauke;Shi Tuo |
分类号 |
C12N1/13;C12P7/06;C12N1/12;C12N15/74 |
主分类号 |
C12N1/13 |
代理机构 |
|
代理人 |
Ebert Lawrence B.;Jepson Suzanne G.;Lorenz David J. |
主权项 |
1. An ethanologenic recombinant cyanobacterium comprising a recombinant alcohol dehydrogenase gene and a heterologous pyruvate decarboxylase gene wherein said alcohol dehydrogenase gene is operably linked to a first promoter and wherein said pyruvate decarboxylase gene is operably linked to a second promoter and wherein said second promoter is a Co2+ inducible promoter or a Zn2+ inducible promoter. |
地址 |
Fort Meyers FL US |