发明名称 |
Spektrometer forsynet med pulseret ionkilde og transmissionsanordning til dæmpning af ionbevægelse og fremgangsmåde til anvendelse deraf |
摘要 |
A method and apparatus are provided for providing an ion transmission device or interface between an ion source and a spectrometer. The ion transmission device can include a multipole rod set and includes a damping gas, to damp spatial and energy spreads of ions generated by a pulsed ion source. The multipole rod set has the effect of guiding the ions along an ion path, so that they can be directed into the inlet of a mass spectrometer. The invention has particular application to MALDI (matrix-assisted laser desorption/ionization) ion sources, which produce a small supersonic jet of matrix molecules and ions, which is substantially non-directional, and can have ions travelling in all available directions from the source and having a wide range of energy spreads. The ion transmission device can have a number of effects, including: substantially spreading out the generated ions along an ion axis to generate a quasi-continuous beam; reducing the energy spread of ions emitted from the source; and at least partially suppressing unwanted fragmentation of analyte ions. Consequently, a number of pulses of ions can be delivered to the time-of-flight or other spectrometer, for each cycle of the ion generation. |
申请公布号 |
DK1050061(T4) |
申请公布日期 |
2017.01.23 |
申请号 |
DK19990900849T |
申请日期 |
1999.01.25 |
申请人 |
University of Manitoba |
发明人 |
KRUTCHINSKY, Andrew, N.;LOBODA, Alexandre, V.;SPICER, Victor, L.;ENS, Erich, W.;STANDING, Kenneth, G. |
分类号 |
H01J49/06;H01J49/42;H01J1/00;H01J49/10;H01J49/40 |
主分类号 |
H01J49/06 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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