发明名称 |
MACROCYCLIC PROLINE DERIVED HCV SERINE PROTEASE INHIBITORS HCV |
摘要 |
The present invention discloses compounds of Formula I or pharmaceutically acceptable salts, esters, or prodrugs thereof: which inhibit serine protease activity, particularly the activity of hepatitis C virus (HCV) NS3-NS4A protease. Consequently, the compounds of the present invention interfere with the life cycle of the hepatitis C virus and are also useful as antiviral agents. The present invention further relates to pharmaceutical compositions comprising the aforementioned compounds for administration to a subject suffering from HCV infection. The invention also relates to methods of treating an HCV infection in a subject by administering a pharmaceutical composition comprising the compounds of the present invention. |
申请公布号 |
HK1186979(A1) |
申请公布日期 |
2017.01.20 |
申请号 |
HK20140100080 |
申请日期 |
2014.01.06 |
申请人 |
Enanta Pharmaceuticals Inc. |
发明人 |
OR, Yat Sun;MA, Jun;WANG, Guoqiang;LONG, Jiang;WANG, Bin |
分类号 |
C07K;A61K |
主分类号 |
C07K |
代理机构 |
|
代理人 |
|
主权项 |
|
地址 |
|