发明名称 |
ANTIBODIES DIRECTED TO ANGIOPOIETIN-2 AND USES THEREOF -2 |
摘要 |
Antibodies directed to the antigen Ang-2 and uses of such antibodies are described. In particular, fully human monoclonal antibodies directed to the antigen Ang-2. Nucleotide sequences encoding, and amino acid sequences comprising, heavy and light chain immunoglobulin molecules, particularly sequences corresponding to contiguous heavy and light chain sequences spanning the framework regions and/or complementary determining regions (CDRs), specifically from FR1 through FR4 or CDR1 through CDR3. Hybridomas or other cell lines expressing such immunoglobulin molecules and monoclonal antibodies. |
申请公布号 |
HK1217713(A1) |
申请公布日期 |
2017.01.20 |
申请号 |
HK20160105651 |
申请日期 |
2016.05.17 |
申请人 |
ASTRAZENECA AB |
发明人 |
GREEN, Larry L. LL;ZHOU, Qing Q;KEYT, Bruce, A. BA;YANG, Xiao-dong X;EMERY, Stephen, Charles SC;BLAKEY, David C. DC |
分类号 |
C07K;A61K;A61P;C12N |
主分类号 |
C07K |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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