NOVEL RECOVERY AND RECYCLING PROCESS OF RACEMIC 4-(4-DIMETHYLAMINO)-1-(4'-FLUOROPHENYL)-1-(HYDROXYBUTYL)-3-(HYDROXYMETHYL)-BENZONITRILE
摘要
Disclosed herein is a novel recovery and recycling process of racemic 4-(4- dimethylamino)-1-(4'-fluorophenyl)-1-(hydroxybutyl)-3-(hydroxymethyl)- benzonitrile (hereinafter referred as cyanodiol). The racemic cyanodiol is an intermediate useful for preparation of Citalopram, Escitalopram or pharmaceutically acceptable salts thereof.
申请公布号
WO2017009866(A1)
申请公布日期
2017.01.19
申请号
WO2016IN50231
申请日期
2016.07.11
申请人
IPCA LABORATORIES LIMITED
发明人
REGURI, Buchi Reddy;PRASAD, Ashok;RAWAT, Ajay Singh;RAJPUT, Sandip;SANTAN, Rohit B