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1. A compound represented by formula (1) or a pharmacologically acceptable salt thereof: wherein A is O, S, or N—R6; the ring G is a 5- or 6-membered aromatic ring that contains one to three heteroatoms consisting of O, S, and N as constituent atoms; R1 is each independently a hydrogen atom, a halogen atom, a cyano group, an optionally substituted 3- to 8-membered cyclic amino group, an optionally substituted C1-6 alkyl group, with the proviso that an unsubstituted methyl group and a C1-6 alkyl group substituted with one dimethyl amino group or one chlorine atom are excluded, an optionally substituted C3-10 cycloalkyl group, an optionally substituted C1-6 alkenyl group, an optionally substituted C1-6 alkynyl group, an optionally substituted C6-10 aryl group, an optionally substituted 5- to 12-membered monocyclic or polycyclic heterocyclic group, an optionally substituted C1-6 alkylcarbonyl group, an optionally substituted C3-10 cycloalkylcarbonyl group, an optionally substituted C6-10 arylcarbonyl group, an optionally substituted 5- to 12-membered monocyclic or polycyclic heterocyclylcarbonyl group, a carboxyl group, an optionally substituted C3-10 cycloalkyloxycarbonyl group, an optionally substituted C6-10 aryloxycarbonyl group, an optionally substituted 5- to 12-membered monocyclic or polycyclic heterocyclyloxycarbonyl group, an optionally substituted aminocarbonyl group, an optionally substituted 3- to 8-membered cyclic aminocarbonyl group, an optionally substituted C1-6 alkylthio group, an optionally substituted C3-10 cycloalkylthio group, an optionally substituted C6-10 arylthio group, an optionally substituted 5- to 12-membered monocyclic or polycyclic heterocyclylthio group, a sulfinate group, an optionally substituted C1-6 alkylsulfinyl group, an optionally substituted C3-10 cycloalkylsulfinyl group, an optionally substituted C6-10 arylsulfinyl group, an optionally substituted 5- to 12-membered monocyclic or polycyclic heterocyclylsulfinyl group, an optionally substituted aminosulfinyl group, an optionally substituted 3- to 8-membered cyclic aminosulfinyl group, a sulfonate group, an optionally substituted C1-6 alkylsulfonyl group, an optionally substituted C3-10 cycloalkylsulfonyl group, an optionally substituted C6-10 arylsulfonyl group, an optionally substituted 5- to 12-membered monocyclic or polycyclic heterocyclylsulfonyl group, an optionally substituted aminosulfonyl group, or an optionally substituted 3- to 8-membered cyclic aminosulfonyl group; R2 is each independently a hydrogen atom, a halogen atom, a cyano group, a substituted amino group, an optionally substituted 3- to 8-membered cyclic amino group, an optionally substituted C1-6 alkyl group with the proviso that an unsubstituted methyl group is excluded, an optionally substituted C3-10 cycloalkyl group, an optionally substituted C1-6 alkenyl group, an optionally substituted C1-6 alkynyl group, an optionally substituted C6-10 aryl group, an optionally substituted 5- to 12-membered monocyclic or polycyclic heterocyclic group, an optionally substituted C1-6 alkylcarbonyl group, an optionally substituted C3-10 cycloalkylcarbonyl group, an optionally substituted C6-10 arylcarbonyl group, an optionally substituted 5- to 12-membered monocyclic or polycyclic heterocyclylcarbonyl group, a carboxyl group, an optionally substituted C1-6 alkoxycarbonyl group, an optionally substituted C3-10 cycloalkyloxycarbonyl group, an optionally substituted C6-10 aryloxycarbonyl group, an optionally substituted 5- to 12-membered monocyclic or polycyclic heterocyclyloxycarbonyl group, an optionally substituted aminocarbonyl group, an optionally substituted 3- to 8-membered cyclic aminocarbonyl group, an optionally substituted C1-6 alkylthio group, an optionally substituted C3-10 cycloalkylthio group, an optionally substituted C6-10 arylthio group, an optionally substituted 5- to 12-membered monocyclic or polycyclic heterocyclylthio group, a sulfinate group, an optionally substituted C1-6 alkylsulfinyl group, an optionally substituted C3-10 cycloalkylsulfinyl group, an optionally substituted C6-10 arylsulfinyl group, an optionally substituted 5- to 12-membered monocyclic or polycyclic heterocyclylsulfinyl group, an optionally substituted aminosulfinyl group, an optionally substituted 3- to 8-membered cyclic aminosulfinyl group, a sulfonate group, an optionally substituted C1-6 alkylsulfonyl group, an optionally substituted C3-10 cycloalkylsulfonyl group, an optionally substituted C6-10 arylsulfonyl group, an optionally substituted 5- to 12-membered monocyclic or polycyclic heterocyclylsulfonyl group, an optionally substituted aminosulfonyl group, or an optionally substituted 3- to 8-membered cyclic aminosulfonyl group; R3, R4, or R5 is each independently a hydrogen atom, a halogen atom, a cyano group, an hydroxyl group, an optionally substituted amino group, an optionally substituted C1-6 alkyl group, an optionally substituted C3-10 cycloalkyl group, an optionally substituted C1-6 alkenyl group, an optionally substituted C1-6 alkynyl group, an optionally substituted C1-6 alkoxy group, an optionally substituted C6-10 aryl group, an optionally substituted 5- to 12-membered monocyclic or polycyclic heterocyclic group, an optionally substituted C1-6 alkylcarbonyl group, an optionally substituted C3-10 cycloalkylcarbonyl group, an optionally substituted C6-10 arylcarbonyl group, an optionally substituted 5- to 12-membered monocyclic or polycyclic heterocyclylcarbonyl group, a carboxyl group, an optionally substituted C1-6 alkoxycarbonyl group, an optionally substituted C3-10 cycloalkyloxycarbonyl group, an optionally substituted C6-10 aryloxycarbonyl group, an optionally substituted 5- to 12-membered monocyclic or polycyclic heterocyclyloxycarbonyl group, an optionally substituted aminocarbonyl group, an optionally substituted C1-6 alkylthio group, an optionally substituted C3-10 cycloalkylthio group, an optionally substituted C6-10 arylthio group, an optionally substituted 5- to 12-membered monocyclic or polycyclic heterocyclylthio group, a sulfinate group, an optionally substituted C1-6 alkylsulfinyl group, an optionally substituted C3-10 cycloalkylsulfinyl group, an optionally substituted C6-10 arylsulfinyl group, an optionally substituted 5- to 12-membered monocyclic or polycyclic heterocyclylsulfinyl group, an optionally substituted aminosulfinyl group, a sulfonate group, an optionally substituted C1-6 alkylsulfonyl group, an optionally substituted C3-10 cycloalkylsulfonyl group, an optionally substituted C6-10 arylsulfonyl group, an optionally substituted 5- to 12-membered monocyclic or polycyclic heterocyclylsulfonyl group, or an optionally substituted aminosulfonyl group, R6 is a hydrogen atom, an optionally substituted C1-6 alkyl group, an optionally substituted C3-10 cycloalkyl group, an optionally substituted C6-10 aryl group, an optionally substituted 5- to 12-membered monocyclic or polycyclic heterocyclic group, an optionally substituted C1-6 alkylcarbonyl group, an optionally substituted C3-10 cycloalkylcarbonyl group, an optionally substituted C6-10 arylcarbonyl group, an optionally substituted 5- to 12-membered monocyclic or polycyclic heterocyclylcarbonyl group, an optionally substituted C1-6 alkoxycarbonyl group, an optionally substituted C3-10 cycloalkyloxycarbonyl group, an optionally substituted C6-10 aryloxycarbonyl group, an optionally substituted 5- to 12-membered monocyclic or polycyclic heterocyclyloxycarbonyl group, an optionally substituted C1-6 alkylsulfinyl group, an optionally substituted C3-10 cycloalkylsulfinyl group, an optionally substituted C6-10 arylsulfinyl group, an optionally substituted 5- to 12-membered monocyclic or polycyclic heterocyclylsulfinyl group, an optionally substituted C1-6 alkylsulfonyl group, an optionally substituted C3-10 cycloalkylsulfonyl group, an optionally substituted C6-10 arylsulfonyl group, or an optionally substituted 5- to 12-membered monocyclic or polycyclic heterocyclylsulfonyl group, with the proviso that in the formula (1),
a compound in which R1 and R2 are both hydrogen atoms,a compound in which when A is O, the ring G is a furan ring or an imidazole ring,a compound in which when A is S, the ring G is a thiophene ring or an imidazole ring,a compound in which when A is N—R6, the ring G is a pyrrole ring, a pyrazole ring, or an imidazole ring,an 2-isopropylfuro[3,2-g]quinoline-4,9-dione compound, andan ethyl 4,8-dioxo-2,7-diphenyl-4,8-dihydrothieno[2,3-f]benzofuran-6-carboxylate compound are excluded. |
