发明名称 ANTI-INFLAMMATORY PEPTIDES, AND USES THEREOF
摘要 An anti-inflammatory peptide comprises an anti-inflammatory fragment of a protein selected from SEQUENCE ID NO's: 1 to 16, the anti-inflammatory fragment being 7 to 37 amino acids in length and having a charge of between -9 and +3; wherein the c-terminal amino acid is not cysteine (C) or methionine (M), and the n-terminal amino acid is not cysteine (C), histidine (H), proline (P) or threonine (T). The anti-inflammatory fragment does not contain cysteine (C). The anti-inflammatory fragment is from a region of the proteins of SEQUENCE ID NO's: 1 to 16, which region is characterised by being 17 to 109 amino acids in length and having a charge of between -6 and +4, wherein the c-terminal amino acid of the region is not aspartic acid (D), phenylalanine (F), methionine (M) or tryptophan (W), and the n-terminal amino acid of the region is not aspartic acid (D), histidine (H), methionine (M), proline (P) or tryptophan (W). Examples of peptides are provided in SEQUENCE ID NO's: 71 to 221.
申请公布号 WO2017009484(A1) 申请公布日期 2017.01.19
申请号 WO2016EP67090 申请日期 2016.07.18
申请人 NURITAS LIMITED 发明人 KHALDI, Nora;LOPEZ, Cyril;ADLEFIO, Alessandro
分类号 A61K38/01;C07K14/415 主分类号 A61K38/01
代理机构 代理人
主权项
地址