发明名称 METHOD FOR IN-GEL VISUAL DETECTION OF BIOANALYTES
摘要 The present invention relates to a method for in-gel visual detection and quantitative detection of proteins in activity based protein profiling (ABPP) using horseradish peroxidase mimic FeIII-TAML complex of ligand as a catalytic probe. The invention further relates to kit comprising compounds of formula (I) and method for the detection of bioanalytes using kit comprising compounds of formula (I).
申请公布号 US2017016854(A1) 申请公布日期 2017.01.19
申请号 US201615202286 申请日期 2016.07.05
申请人 Council of Scientific & Industrial Research 发明人 Gupta Sayam Sen;Kumari Sushma;Panda Chakadola
分类号 G01N27/447;G01N33/68;C07F15/02;C12Q1/37 主分类号 G01N27/447
代理机构 代理人
主权项 1. A method for in-gel visual detection and quantitative detection of a bioanalyte comprising: contacting the bioanalyte with a compound of formula (I) wherein, X is a mono ionic ligand, selected from chloro, bromo or iodo or is a neutral ligand, and R1, R2, R3, R4, R5, R6, R7, R8 and R9 are the same or are different and are selected form the group consisting of hydrogen, alkyl, alkenyl, alkynyl, aryl, alkoxy, phenoxy, halogen, halogenated alkyl, halogenated alkenyl, halogenated alkynyl, a substituted or unsubstituted cycloalkyl ring, substituted or unsubstituted cycloalkenyl ring, a substituted or unsubstituted saturated heterocyclic ring, a substituted or unsubstituted unsaturated heterocyclic ring, carboxylic acid, carboxylic acid ester, carboxylic acid halides, amines, nitro, and nitrile etc., and, wherein P is a cation selected from Li, Na, K, Et4Nor Ph4P.
地址 New Delhi IN