| 发明名称 |
Tumor selective macropinocytosis-dependent rapidly internalizing antibodies |
| 摘要 |
Methods are provided for identifying and selecting antibodies that are internalized into cells via the macropinocytosis pathway. Additionally antibodies that are internalized via this pathway are provided as well as immunoconjugates comprising such antibodies. |
| 申请公布号 |
AU2015287749(A1) |
申请公布日期 |
2017.01.19 |
| 申请号 |
AU20150287749 |
申请日期 |
2015.07.09 |
| 申请人 |
The Regents of The University of California |
发明人 |
Liu, Bin |
| 分类号 |
C07K16/30;A61K31/47;A61K31/7088;A61K49/00;A61P35/00;C40B40/10;G01N33/533;G01N33/574 |
主分类号 |
C07K16/30 |
| 代理机构 |
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代理人 |
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| 地址 |
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