CHD Risk Stratification Evaluations for Subjects with High Levels of Large HDL-P

摘要

Embodiments of the invention are directed to methods, systems and computer programs that provide improved risk stratification for people having elevated large HDL-P using at least one defined HDL risk interaction parameter.

主权项

1. A method of determining whether a subject with elevated concentrations of very large high density lipoprotein (HDL) particles (HDL-P) is at increased risk for a cardiac event and/or CHD, comprising:
programmatically calculating at least one HDL interaction risk parameter associated with HDL content of a blood plasma or serum sample of the subject, the at least one HDL interaction risk parameter comprising at least two of HPVS, HPML, and HPVL, where HPVS is a concentration of very small HDL-P subclasses, HPML is a concentration of medium and large HDL-P subclasses, and HPVL is a concentration of very large HDL-P subclasses.