发明名称 |
FORMULATIONS FOR INHIBITION FOR PCSK9 FOR THE TREATMENT OF HYPERCHOLESTEROLEMIA |
摘要 |
Described herein are pharmaceutical formulations for the treatment of hypercholesterolemia, comprising nanoparticles having a polymeric hydrophobic core which is associated with an inhibitor of PCSK9. The inhibitor may be EGF-A, EGF-B, or an siRNA. Preferred polymers include chitosan. The nanoparticle may further include a hydrophilic shell coating the core. |
申请公布号 |
EP3093028(A3) |
申请公布日期 |
2017.01.18 |
申请号 |
EP20160164949 |
申请日期 |
2016.04.12 |
申请人 |
Heart Biotech Limited |
发明人 |
YACOUB, Magdi Habib;EL SHERBINY, Ibrahim |
分类号 |
A61K31/7105;A61K38/18;A61P9/00 |
主分类号 |
A61K31/7105 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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