发明名称 USE OF OIL AND WATER EMULSIONS FOR INCREASING B CELL RESPONSES WITH MODIFIED VACCINIA ANKARA VIRUS
摘要 The invention relates to compositions, uses, and methods for inducing an immune response against a vaccinia virus. The addition of an oil and water emulsion to MVA can vastly increase the B cell response and particularly neutralizing antibodies against vaccinia virus and encoded recombinant antigens. Thus, the addition of an oil and water emulsion to MVA can increase the protective immune response. The invention encompasses administering a dose of an MVA in an oil and water emulsion to an animal, especially a human.
申请公布号 EP3116541(A1) 申请公布日期 2017.01.18
申请号 EP20150721582 申请日期 2015.03.12
申请人 Bavarian Nordic A/S 发明人 CHEMINAY, Cédric;STEIGERWALD, Robin;VOLKMANN, Ariane
分类号 A61K39/285 主分类号 A61K39/285
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