发明名称 MTOR KINASE INHIBITORS FOR ONCOLOGY INDICATIONS AND DISEASES ASSOCIATED WITH THE MTOR/P13K/AKT PATHWAY
摘要 Provided herein are Heteroaryl Compounds having the following structure: wherein R 1 -R 3 are as defined herein, compositions comprising an effective amount of a Heteroaryl Compound and a Heteroaryl Compound provided herein for use in a method of treating or preventing cancer, inflammatory conditions, immunological conditions, neurodegenerative diseases, diabetes, obesity, neurological disorders, age-related diseases, or cardiovascular conditions.
申请公布号 EP2358718(B1) 申请公布日期 2017.01.18
申请号 EP20090759827 申请日期 2009.10.27
申请人 Signal Pharmaceuticals, LLC 发明人 ELSNER, Jan;HARRIS, Roy, L.;LEE, Branden;MORTENSEN, Deborah;PACKARD, Garrick;PAPA, Patrick;PERRIN-NINKOVIC, Sophie;RIGGS, Jennifer;SANKAR, Sabita;SAPIENZA, John;SHEVLIN, Graziella;TEHRANI, Lida;XU, Weiming;ZHAO, Jingjing;PARNES, Jason;MADAKAMUTIL Loui;FULTZ Kimberly;NARLA, Rama K.
分类号 C07D487/04;A61K31/4985;A61P35/00 主分类号 C07D487/04
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