发明名称 |
TREATING DISEASES USING NITRIC OXIDE RELEASING SOLUTIONS |
摘要 |
The present invention relates to a liquid nitric oxide releasing solution (NORS) comprised of at least one nitric oxide releasing compound and at least one acidifying agent, wherein the NORS provides an extended release of a therapeutically effective amount of nitric oxide gas (gNO). The present invention also relates to a liquid NORS comprised of at least one nitrite compound having a concentration of no greater than about 0.5% w/v and at least one acidifying agent, wherein the NORS releases a therapeutically effective amount of gNO. The present invention also relates to a method for the treatment of a wound in a human, the method comprising administering to the human a liquid NORS comprised of at least one nitric oxide releasing compound and at least one acidifying agent, wherein the NORS provides an extended release of a therapeutically effective amount of gNO. The present invention also relates to a method for the treatment, prevention, or reduction of incidence of a disease or disorder in a human in need thereof, the method comprising administering to the human a liquid NORS comprised of at least one nitrite compound at a concentration of no greater than about 0.5% w/v and at least one acidifying agent, wherein the NORS releases a therapeutically effective amount of gNO. |
申请公布号 |
EP3116484(A1) |
申请公布日期 |
2017.01.18 |
申请号 |
EP20150761353 |
申请日期 |
2015.03.10 |
申请人 |
12th Man Technologies, Inc. |
发明人 |
STENZLER, Alex;MILLER, Christopher C.;REGEV-SHOSHANI, Gilly |
分类号 |
A61K9/72;A61M35/00;C01B21/24 |
主分类号 |
A61K9/72 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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