Compounds for the treatment of bacterial and parasitic infections which are hybrid compounds of compounds having antibacterial or antiparasitic activity and compounds that decrease the absorption of the hybrid compound from the gastrointestinal tract. The compounds are preferably for use against C. difficile infections and comprise a hybrid molecule of an anti-C. difficile compound such as a nitroimidazole and a tetramic acid derivative.
申请公布号
EP3116499(A1)
申请公布日期
2017.01.18
申请号
EP20150762125
申请日期
2015.03.12
申请人
Board of Regents, The University of Texas System;St. Jude Children's Research Hospital, Inc.
发明人
LEE, Richard E.;CHERIAN, Philip T.;HURDLE, Julian, G.;WU, Xiaoqian