| 发明名称 | Genes and proteins for alkanoyl-CoA synthesis | ||
| 摘要 | Polypeptides having alkanoyl-CoA activity have been identified and characterized, as have nucleic acids encoding these polypeptides. Expression or over-expression of the nucleic acids alters levels of cannabinoid compounds in organisms. The polypeptides may be used in vivo or in vitro to produce cannabinoid compounds. | ||
| 申请公布号 | US9546362(B2) | 申请公布日期 | 2017.01.17 |
| 申请号 | US201214232465 | 申请日期 | 2012.07.13 |
| 申请人 | National Research Council of Canada;University of Saskatchewan | 发明人 | Page Jonathan E.;Stout Jason M. |
| 分类号 | C12N9/00;C12N9/10;C12N9/90;C12N15/82;C12P7/42;C12P17/06 | 主分类号 | C12N9/00 |
| 代理机构 | Bereskin & Parr LLP | 代理人 | Bereskin & Parr LLP ;De Luca Carmela |
| 主权项 | 1. A process of decreasing levels of a cannabinoid compound in a cannabis plant, cannabis cell or cannabis tissue, the process comprising using a RNAi nucleic acid molecule comprising a nucleotide sequence complementary to a portion of SEQ ID NO: 1 or SEQ ID NO: 3, to silence in the cannabis plant, cannabis cell or cannabis tissue a gene that encodes an enzyme that catalyzes synthesis of an alkanoyl-CoA, in comparison to a similar variety of organism, cell or tissue grown under similar conditions but without the use of the nucleic acid molecule for silencing. | ||
| 地址 | Ottawa CA | ||