| 发明名称 | Anti-Siglec-8 antibodies and methods of use thereof | ||
| 摘要 | The invention provides humanized anti-Siglec-8 antibodies and their use in treating and preventing eosinophil-mediated disorders and/or mast cell-mediated disorders, as well as compositions and kits comprising the humanized anti-Siglec-8 antibodies. | ||
| 申请公布号 | US9546215(B2) | 申请公布日期 | 2017.01.17 |
| 申请号 | US201414565370 | 申请日期 | 2014.12.09 |
| 申请人 | ALLAKOS INC. | 发明人 | Bebbington Christopher R.;Falahati Rustom;Sousa Fernandes Carolina Rita;Matthews David John;Tomasevic Nenad;Williams Jason;Leung John |
| 分类号 | C07K16/28 | 主分类号 | C07K16/28 |
| 代理机构 | Morrison & Foerster LLP | 代理人 | Morrison & Foerster LLP |
| 主权项 | 1. An antibody that binds to a human Siglec-8, wherein the antibody comprises a heavy chain variable region and a light chain variable region, wherein the heavy chain variable region comprises the amino acid sequence of SEQ ID NO:6 or the light chain variable region comprises the amino acid sequence of SEQ ID NOs:16 or 21. | ||
| 地址 | San Carlos CA US | ||