Preparation of ertapenem intermediates

摘要

The present invention relates to the preparation of compounds, in particular to the preparation of compounds which may be used as intermediates for the preparation of antibiotics, preferably carbapenem antibiotics, more preferably ertapenem, and salts thereof.

主权项

1. A process for the preparation of a compound of formula (VI) or a salt thereof, comprising a step d) of converting a crystalline compound of formula (I) or a solvate thereof to the compound of formula (VI); wherein the PG residues are each and independently a protective group, which is capable of protecting a carboxylic acid function.