Dialysis system with ultrafiltration control

摘要

Systems and methods are disclosed for performing hemodialysis that include fluid handling systems that provide accurate control over the type and level of hemodialysis being performed. The system includes a first pump for pumping dialysate into a dialyzer and a second pump for pumping dialysate out of the dialyzer. The system also includes a third pump that provides improved control of a level of ultrafiltration, hemodiafiltration, or both.

主权项

1. A method of calibrating a dialysis system comprising a dialyzer, a dialysate inlet pump, an inlet fluid flow pathway extending from the dialysate inlet pump to the dialyzer, a dialysate outlet pump, an outlet fluid flow pathway extending from the dialyzer to the dialysate outlet pump, the dialysate outlet pump being the only pump positioned for pumping dialysate out of and away from the dialyzer through the outlet fluid flow pathway, a bypass fluid flow pathway extending from the inlet fluid flow pathway to the outlet fluid flow pathway and bypassing the dialyzer, the method comprising:
flowing fluid from the dialysate inlet pump through the bypass fluid flow pathway to the dialysis outlet pump; comparing pressure of the fluid in the inlet fluid flow pathway to pressure of the fluid in the outlet fluid flow pathway; based on a result of the comparing step, adjusting a pump rate of the dialysate inlet pump or the dialysate outlet pump to achieve a balanced flow rate through the inlet fluid flow pathway and the outlet fluid flow pathway; and after the adjusting step, controlling the pump rate of the dialysate inlet pump or the dialysate outlet pump to pump fluid from the dialysate inlet pump through the inlet fluid flow pathway to the dialyzer at an inlet flow rate and through the outlet fluid flow pathway to the dialysate outlet pump from the dialyzer at an outlet flow rate different than the inlet flow rate.