发明名称 Fusion protein having transcription factor transactivation-regulating domain and protein transduction domain, and transcription factor function inhibitor comprising the same
摘要 This invention relates to a fusion protein comprising the TMD of the transcription factor and PTD, an inhibitor for transcription factor function comprising the same, and a method for producing the same. Various diseases associated with malfunctions or defects of the transcription factor are effectively treated using the fusion protein according to the present invention.
申请公布号 US9546221(B2) 申请公布日期 2017.01.17
申请号 US201113818062 申请日期 2011.08.19
申请人 Lee San-Kyou;Park Tae Yoon;Seong Ye Kyung;Cho Jen Young;Park Jong Hyun;Yang Sang Hwa 发明人 Lee San-Kyou;Park Tae Yoon;Seong Ye Kyung;Cho Jen Young;Park Jong Hyun;Yang Sang Hwa
分类号 C07K19/00;C07K14/47;C12N15/62 主分类号 C07K19/00
代理机构 Mintz Levin Cohn Ferris Glovsky and Popeo, P.C. 代理人 Mintz Levin Cohn Ferris Glovsky and Popeo, P.C. ;Kim Kongsik;Emmons Richard B.
主权项 1. A fusion protein comprising a transcription modulating domain (TMD) of a transcription factor and a protein transduction domain (PTD), wherein the fusion protein is SEQ ID NO:7, to treat a disease selected from the group consisting of multiple sclerosis and rheumatoid arthritis.
地址 Seoul KR