发明名称 |
Fusion protein having transcription factor transactivation-regulating domain and protein transduction domain, and transcription factor function inhibitor comprising the same |
摘要 |
This invention relates to a fusion protein comprising the TMD of the transcription factor and PTD, an inhibitor for transcription factor function comprising the same, and a method for producing the same. Various diseases associated with malfunctions or defects of the transcription factor are effectively treated using the fusion protein according to the present invention. |
申请公布号 |
US9546221(B2) |
申请公布日期 |
2017.01.17 |
申请号 |
US201113818062 |
申请日期 |
2011.08.19 |
申请人 |
Lee San-Kyou;Park Tae Yoon;Seong Ye Kyung;Cho Jen Young;Park Jong Hyun;Yang Sang Hwa |
发明人 |
Lee San-Kyou;Park Tae Yoon;Seong Ye Kyung;Cho Jen Young;Park Jong Hyun;Yang Sang Hwa |
分类号 |
C07K19/00;C07K14/47;C12N15/62 |
主分类号 |
C07K19/00 |
代理机构 |
Mintz Levin Cohn Ferris Glovsky and Popeo, P.C. |
代理人 |
Mintz Levin Cohn Ferris Glovsky and Popeo, P.C. ;Kim Kongsik;Emmons Richard B. |
主权项 |
1. A fusion protein comprising a transcription modulating domain (TMD) of a transcription factor and a protein transduction domain (PTD), wherein the fusion protein is SEQ ID NO:7, to treat a disease selected from the group consisting of multiple sclerosis and rheumatoid arthritis. |
地址 |
Seoul KR |