System design and method for verifying 3D dosimetric imaging of charged particles in media

摘要

A method of verifying therapeutic beam delivery accuracy by ultrasound tomographic imaging to map three dimensional (3D) dose through the detection of ionizing radiation induced thermo-acoustic signal from the proton beam.

主权项

1. A method of verification of the accuracy of delivery of a charged particle beam to a tumor in a human body, the method comprising:
irradiating the tumor with the charged particle beam; receiving an ultrasound signal generated due to the irradiation of the tumor by the charged particle beam; mapping a three dimensional source of the ultrasound signal; wherein the ultrasound signal is formed at the source in the human body due to thermo-acoustic mechanism of a stress wave generation from energy loss of charged particles associated with the charged particle beam; and determining a value of falloff of the ultrasound signal corresponding to a distal edge of the charged particle beam associated with a Bragg peak.