Carrier comprising a vitamin E derivative

摘要

A pharmaceutical composition is provided comprising a vitamin E derivative, an anionic phopholipid-binding protein, an anionic phospholipid and a sterol. Also provided is a method for preparing a composition for delivering a cargo to a subject comprising a) forming liposomes from a vitamin E derivative, an anionic phospholipid-binding protein such as annexin, an anionic phospholipid such as phosphatidylserine and a sterol; and b) encapsulating the cargo in the liposomal composition.

主权项

1. A pharmaceutical composition comprising a vitamin E derivative, an anionic phospholipid-binding protein, an anionic phospholipid and a sterol, wherein the vitamin E derivative, anionic phospholipid and sterol form a lipid membrane and wherein the anionic phospholipid-binding protein is bound to the surface of the lipid membrane.