| 发明名称 | Treatment of mucositis with immunoglobulin | ||
| 摘要 | The invention relates to compositions comprising immunoglobulin for use in the treatment of mucositis by topical application. In particular, the invention relates to compositions comprising J chain-containing IgA and secretory component for the treatment of mucositis. | ||
| 申请公布号 | US9546209(B2) | 申请公布日期 | 2017.01.17 |
| 申请号 | US201314380457 | 申请日期 | 2013.03.08 |
| 申请人 | CSL Behring AG;Universitaet Bern | 发明人 | Aebi Christoph;Lueer Sonja Christina;Schaub Alexander;Miescher Sylvia;Zuercher Adrian;Vonarburg Cédric Pierre |
| 分类号 | A61K39/00;A61K39/395;A61K49/00;C07K16/00;C07K16/14;C07K16/06;C07K16/12 | 主分类号 | A61K39/00 |
| 代理机构 | Birch, Stewart, Kolasch & Birch, LLP | 代理人 | Birch, Stewart, Kolasch & Birch, LLP |
| 主权项 | 1. A method for the prevention or treatment of mucositis of the alimentary tract comprising: administering topically to a human subject an effective amount of a composition comprising an effective amount of immunoglobulin derived from pooled human plasma to prevent or treat mucositis of the alimentary tract, with the proviso that the plasma derived immunoglobulin is not a pure anti-TNF antibody or immunoglobulin enriched for anti-TNF or purified from a human or animal donor immunized with TNF-α. | ||
| 地址 | Bern CH | ||