Systems and methods for endoluminal valve creation

摘要

A device for manipulating tissue at a vessel includes an elongated member having a proximal end and a distal end, a guide member at the distal end of the elongated member, the guide member having a blunt distal tip for engagement against an interior wall of the vessel, and a tissue cutting device at the distal end of the elongated member, wherein the tissue cutting device has a sharp tip that is proximal to the blunt distal tip of the guide member.

主权项

1. A method for gaining controlled access to an interior portion of a wall of a blood vessel, the method comprising:
providing an elongated member having a longitudinal axis, a proximal portion and a distal portion having (a) a wall tensioning mechanism, and (b) a slanted surface spanning a length of the distal portion in a longitudinal direction and extending across a cross-section of the elongated member, wherein the slanted surface forms an acute angle with respect to the longitudinal axis; positioning the distal portion of the elongated member at a treatment site within a lumen of the blood vessel such that the elongated member extends along a longitudinal axis of the blood vessel; while at least the length of the distal portion remains extending along the longitudinal axis of the blood vessel, positioning the slanted surface in apposition with a first portion of the blood vessel wall at the treatment site, thereby conforming the portion to the slanted surface to position the portion at the acute angle; extending a tissue penetrating element from a port on the slanted surface to penetrate an interior surface of the blood vessel wall along the portion in apposition with the slanted surface; and expanding the wall tensioning mechanism at the treatment site such that the wall tensioning mechanism projects radially outwardly away from a side of the distal portion opposite the slanted surface and contacts a second portion of the blood vessel wall circumferentially opposite the first portion while pushing the slanted surface into the first portion of the blood vessel wall such that the first portion of conforms to the slanted surface.