发明名称 |
TRUNKERET L1-PROTEIN AF HUMAN PAPILLOMAVIRUS TYPE 52 |
摘要 |
Provided is a truncated L1 protein of Human Papillomavirus (HPV) Type 52 which, compared to a wild type HPV52 L1 protein, is truncated by 27-42 amino acids at the N-terminal. Also provided are a coding sequence of the truncated HPV52 L1 protein, a virus-like particle (VLP) comprising the protein, and a method of preparing the protein and the VLP using an E. coli expression system. The truncated HPV52 L1 protein and an assembled VLP can be used to prevent an HPV52 infection and a disease caused by HPV52 infection, such as cervical cancer. |
申请公布号 |
DK2589604(T3) |
申请公布日期 |
2017.01.16 |
申请号 |
DK20110800199T |
申请日期 |
2011.07.01 |
申请人 |
Xiamen University;Xiamen Innovax Biotech Co., Ltd. |
发明人 |
LI, Shaowei;MO, Xiaobing;WEI, Minxi;PAN, Huirong;ZHANG, Jun;XIA, Ningshao |
分类号 |
C07K14/025;A61K39/12;A61P31/20;C12N1/21;C12N15/70 |
主分类号 |
C07K14/025 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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