QUINAZOLINE COMPOUND, INTERMEDIATE, PREPARATION METHOD, PHARMACEUTICAL COMPOSITION AND USES THEREOF

摘要

Disclosed are a quinazoline compound, intermediate, preparation method, pharmaceutical composition and use thereof. The quinazoline compound of the present invention has a good inhibitory effect on the protein kinase JAK, and can be used for the preparation of a medicine for the prevention, treatment or adjuvant treatment of a variety of diseases associated with the expression or activity of JAK, in particular tumour diseases and immune diseases.