| 发明名称 |
GENETICALLY ENGINEERED SENSORS FOR IN VIVO DETECTION OF BLEEDING |
| 摘要 |
Provided herein are microorganisms engineered with heme-responsive transcription factors and genetic circuits. Also provided are methods for using engineered microorganisms to sense bleeding events and treat bleeding in vivo. |
| 申请公布号 |
WO2017008018(A1) |
申请公布日期 |
2017.01.12 |
| 申请号 |
WO2016US41520 |
申请日期 |
2016.07.08 |
| 申请人 |
MASSACHUSETTS INSTITUTE OF TECHNOLOGY |
发明人 |
LU, Timothy, Kuan-Ta;MIMEE, Mark, K. |
| 分类号 |
C07K14/245;A61K35/74;C07K14/31;C07K14/335;C12N1/21;C12Q1/02;C12R1/19;G01N33/50 |
主分类号 |
C07K14/245 |
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