发明名称 1-((3S,4R)-4-(3-fluorophenyl)-1-(2-methoxyethyl)pyrrolidin-3-yl)-3-(4-methyl-3-(2-methylpyrimidin-5-yl)-1-phenyl-1h-pyrazol-5-yl)urea as a TrkA kinase inhibitor
摘要 Provided is Compound (I) or a pharmaceutically acceptable salt thereof, which is an inhibitor of TrkA kinase and is useful in the treatment of diseases which can be treated with a TrkA kinase inhibitor such as pain, cancer, inflammation and inflammatory diseases, neurodegenerative diseases, certain infectious diseases, Sjogren's syndrome, endometriosis, diabetic peripheral neuropathy, prostatitis, pelvic pain syndrome, diseases related to an imbalance of the regulation of bone remodeling, and diseases resulting from Connective Tissue Growth Factor aberrant signaling.
申请公布号 AU2015259075(A1) 申请公布日期 2017.01.12
申请号 AU20150259075 申请日期 2015.05.14
申请人 Array BioPharma Inc. 发明人 Allen, Shelley;Andrews, Steven W.;Baer, Brian;Crane, Zackary;Liu, Weidong;Watson, Daniel John
分类号 C07D403/12;A61K31/4155;C07D401/14;C07D403/14;C07D405/14 主分类号 C07D403/12
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