SOLUTION PHASE SYNTHESIS AND CRYSTALLIZATION OF BETA-TURN PEPTIDOMIMETIC CYCLIC SALTS

摘要

The present disclosure relates to methods of preparing and crystallizing β-turn cyclic peptidomimetic salts of formula (I): where R1, R2, R3, R4, R5, R6, R7, R8, R10, X, Y and n are as defined in the specification. The present disclosure provides a more efficient route for preparing a crystalline form of β-turn cyclic peptidomimetic compounds and salts thereof.