发明名称 PHARMACEUTICAL COMPOSITIONS FOR COMBINATION THERAPY
摘要 This invention relates to the use of pharmaceutical compositions comprising a therapeutically effective combination of Tesofensine and Metoprolol for preventing the cardiovascular side effects of Tesofensine, while leaving the robust inhibitory efficacy on food intake and body weight loss unaffected.
申请公布号 US2017007557(A1) 申请公布日期 2017.01.12
申请号 US201615206477 申请日期 2016.07.11
申请人 SANIONA A/S 发明人 Hansen Henrik Bjork;Grunnet Morten;Hjorth Bo;Hyveled-Nielsen Lars;Lassen Jorgen Buus;Sundgreen Claus
分类号 A61K31/138;A61K31/46 主分类号 A61K31/138
代理机构 代理人
主权项 1. A method of treating type 2 diabetes in a human comprising: administering Tesofensine, or a pharmaceutically acceptable salt thereof, to the human; in combination with Metoprolol, or a pharmaceutically acceptable salt thereof, wherein the combination is effective in treating the type 2 diabetes and wherein the combination is effective in preventing or alleviating drug-induced cardiovascular side-effects.
地址 Ballerup DK
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