| 发明名称 |
METHOD FOR THE SYNTHESIS OF PENTOSTATIN |
| 摘要 |
The present invention relates to a method for the stereo-selective production of pentostatin comprising an enzymatic transglycosylation reaction between 6,7-dihydroimidazo-[4,5-d]-[1,3]diazepin-8(3H)-one and a 2'-deoxyribonucleoside, followed by an ruthenium-catalyzed asymmetric transfer hydrogenation. |
| 申请公布号 |
WO2017005784(A1) |
申请公布日期 |
2017.01.12 |
| 申请号 |
WO2016EP65958 |
申请日期 |
2016.07.06 |
| 申请人 |
SYNBIAS PHARMA AG |
发明人 |
ZABUDKIN, Oleksandr;SCHICKANEDER, Christian;MATVIIENKO, Iaroslav;SYPCHENKO, Volodymyr |
| 分类号 |
C12P17/00;C12P19/28 |
主分类号 |
C12P17/00 |
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