Apparatus and Methods for Controlling Application of a Substance to a Substrate

摘要

Apparatus and methods for controlling application of a substance to a substrate involve the use of a functional agent that helps determine the association of a substance with the substrate. The apparatus and methods may utilize jet technology to apply the functional agent directly to the substrate or to an intermediate surface. The substance may be biological substance or a chemical in nature.

主权项

1. An apparatus for applying a biological component to a surface, comprising:
a first substrate; a printhead for jetting a functional agent onto the first substrate in a first pattern; a first apparatus configured to introduce a first principal substance to the functional agent and transfer the first principal substance to a second substrate in the first pattern; and a second apparatus configured to apply a second principal substance to the second substrate; wherein the first principal substance and the second principal substance undergo a biological interaction to determine a second pattern of the second principal substance associated with the second substrate, and wherein the biological interaction is at least one of a cell surface antigen interaction, a protein-nucleic acid interaction, a nucleic acid-nucleic acid interaction, extracellular matrix protein interactions, growth factor interactions, and cell adhesion.