发明名称 |
HETEROCYCLIC DERIVATIVE HAVING TrkA-INHIBITING ACTIVITY |
摘要 |
Provided is a compound having TrkA-inhibiting activity, or a pharmaceutically acceptable salt thereof. The present invention pertains to a compound represented by formula (I) or a pharmaceutically acceptable salt thereof, and a pharmaceutical composition containing same. (In formula (I), -L- represents -C(=X)- or the like, -Z- represents -NR5- or the like, -ZA- represents -NR5A- or the like, B represents a substituted or unsubstituted aromatic carbocyclic group or the like, Y represents a single bond or the like, the ring C represents a substituted or unsubstituted aromatic heterocycle or the like, R2 represents a hydrogen atom or the like, and the group indicated by (AA) represents a group indicated by (BB).) |
申请公布号 |
WO2017006953(A1) |
申请公布日期 |
2017.01.12 |
申请号 |
WO2016JP69968 |
申请日期 |
2016.07.06 |
申请人 |
SHIONOGI & CO., LTD. |
发明人 |
YUKIMASA, Akira;NAKAMURA, Kenichiroh;INAGAKI, Masanao;KANO, Kazuya;FUJIU, Motohiro;YAMAGUCHI, Hiroki;HATA, Kayoko;INOUE, Takatsugu |
分类号 |
C07D231/38;A61K31/4155;A61K31/422;A61K31/433;A61K31/437;A61K31/4439;A61K31/454;A61K31/506;A61K31/519;A61P1/18;A61P13/08;A61P13/10;A61P17/00;A61P19/02;A61P25/02;A61P25/04;A61P29/00;A61P35/00;A61P37/08;C07D405/12;C07D405/14;C07D417/14;C07D471/04;C07D487/04 |
主分类号 |
C07D231/38 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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